human SNX14 shRNA silencing AAV

Name
AAV-h-SNX14-shRNA

Cat No
shAAV-223921

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SNX14.

shAAV-223921

AAV-h-SNX14-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SNX14 (sorting nexin 14). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

RGS-PX2; SCAR20

Description (Vector)

SNX14 encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. The encoded protein also contains a regulator of G protein signaling (RGS) domain. Regulator of G protein signaling family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene ID

57231

Gene Name (Vector)

sorting nexin 14

Gene Symbol

SNX14

HGNC ID

HGNC:14977

ORF Size (aa)

2682

ORF Size (bp)

2682 bp

RefSeq ID

NM_020468

RefSeq Synonyms

NM_153816, NM_020468, NM_001304479, NM_001297614, BC095419, BC068589, BC005110,

Species

human

UniGene ID

Hs.485871

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.