human SLC4A10 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SLC4A10.
shAAV-223511
AAV-h-SLC4A10-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SLC4A10 (solute carrier family 4 member 10). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
NBCn2; NCBE
Description (Vector)
SLC4A10 belongs to a small family of sodium-coupled bicarbonate transporters (NCBTs) that regulate the intracellular pH of neurons, the secretion of bicarbonate ions across the choroid plexus, and the pH of the brain extracellular fluid. The protein encoded by this gene was initially identified as a sodium-driven chloride bicarbonate exchanger (NCBE) though there is now evidence that its sodium/bicarbonate cotransport activity is independent of any chloride ion countertransport under physiological conditions. SLC4A10 is now classified as a member A10 of the SLC4 family of transmembrane solute carriers. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Gene ID
57282
Gene Name (Vector)
solute carrier family 4 member 10
Gene Symbol
SLC4A10
HGNC ID
HGNC:13811
ORF Size (aa)
3267
ORF Size (bp)
3267 bp
RefSeq ID
NM_022058
RefSeq Synonyms
NM_022058, NM_001178016, NM_001178015, BC143714, BC136269,
Species
human
UniGene ID
Hs.333958
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.