human F2RL1 Over-expression AAV

Name 
AAV-h-F2RL1
Cat No 
AAV-208224
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human F2RL1.

AAV-208224
AAV-h-F2RL1

Ready-to-use AAV expressing Human F2RL1 (F2R like trypsin receptor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GPR11; PAR2
Description (Vector)
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence.
Gene ID
2150
Gene Name (Vector)
F2R like trypsin receptor 1
Gene Symbol
F2RL1
HGNC ID
HGNC:3538
ORF Size (aa)
1194
ORF Size (bp)
1194 bp
RefSeq ID
NM_005242
RefSeq Synonyms
NM_005242, BC018130, BC012453,
Species
human
UniGene ID
Hs.154299

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.