human EXOSC1 Over-expression AAV

Name 
AAV-h-EXOSC1
Cat No 
AAV-208185
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human EXOSC1.

AAV-208185
AAV-h-EXOSC1

Ready-to-use AAV expressing Human EXOSC1 (exosome component 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
3'-5' exoribonuclease CSL4 homolog; CGI-108; CSL4; Csl4p; exosomal core protein CSL4; exosome complex component CSL4; Exosome component 1; homolog of yeast exosomal core protein CSL4; p13; SKI4; Ski4p
Description (eCommerce)
EXOSC1 is a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association CSL4 with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46 [taken from NCBI Entrez Gene (Gene ID: 51013)].
Description (Vector)
EXOSC1 encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46.
Gene ID
51013
Gene Name (eCommerce)
exosome component 1
Gene Name (Vector)
exosome component 1
Gene Symbol
EXOSC1
HGNC ID
HGNC:17286
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
588
ORF Size (bp)
588 bp
Protein Name (eCommerce)
Exosome complex component CSL4
RefSeq ID
NM_016046
RefSeq Synonyms
NM_016046, NM_001318366, NM_001318365, NM_001318364, NM_001318363, NM_001318362, BC022067,
Research Areas
Gene Expression,mRNA Binding,RNA Binding,RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
EXOSC1 is a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association CSL4 with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46 [taken from NCBI Entrez Gene (Gene ID: 51013)].
UniGene ID
Hs.632089
UniProt ID (eCommerce)
Q9Y3B2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.