human SETDB2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SETDB2.
shAAV-222743
AAV-h-SETDB2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SETDB2 (SET domain bifurcated 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C13orf4; CLLD8; CLLL8; KMT1F
Description (Vector)
Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 (see MIM 601128) methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 (PubMed 12754510)).(supplied by OMIM, Mar 2008)
Gene ID
83852
Gene Name (Vector)
SET domain bifurcated 2
Gene Symbol
SETDB2
HGNC ID
HGNC:20263
ORF Size (aa)
2124
ORF Size (bp)
2124 bp
RefSeq ID
NM_031915
RefSeq Synonyms
NM_031915, NM_001320699, NM_001160308, BC047434,
Species
human
UniGene ID
Hs.631789
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.