human SERPINB1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SERPINB1.
shAAV-222680
AAV-h-SERPINB1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SERPINB1 (serpin family B member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EI; ELANH2; HEL-S-27; HEL57; LEI; M/NEI; MNEI; PI-2; PI2
Description (Vector)
SERPINB1 is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants.
Gene ID
1992
Gene Name (Vector)
serpin family B member 1
Gene Symbol
SERPINB1
HGNC ID
HGNC:3311
ORF Size (aa)
1140
ORF Size (bp)
1140 bp
RefSeq ID
NM_030666
RefSeq Synonyms
NM_030666, BC009015,
Species
human
UniGene ID
Hs.381167
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.