human SERPINB1 Over-expression AAV

Name 
AAV-h-SERPINB1
Cat No 
AAV-222680
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SERPINB1.

AAV-222680
AAV-h-SERPINB1

Ready-to-use AAV expressing Human SERPINB1 (serpin family B member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EI; ELANH2; HEL-S-27; HEL57; LEI; M/NEI; MNEI; PI-2; PI2
Description (Vector)
SERPINB1 is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants.
Gene ID
1992
Gene Name (Vector)
serpin family B member 1
Gene Symbol
SERPINB1
HGNC ID
HGNC:3311
ORF Size (aa)
1140
ORF Size (bp)
1140 bp
RefSeq ID
NM_030666
RefSeq Synonyms
NM_030666, BC009015,
Species
human
UniGene ID
Hs.381167

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.