human SELENBP1 shRNA silencing AAV

Name
AAV-h-SELENBP1-shRNA

Cat No
shAAV-222518

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SELENBP1.

shAAV-222518

AAV-h-SELENBP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SELENBP1 (selenium binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HEL-S-134P; hSBP; LPSB; SBP56; SP56

Description (Vector)

SELENBP1 encodes a member of the selenium-binding protein family. Selenium is an essential nutrient that exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. The effects of selenium in preventing cancer and neurologic diseases may be mediated by selenium-binding proteins, and decreased expression of this gene may be associated with several types of cancer. The encoded protein may play a selenium-dependent role in ubiquitination/deubiquitination-mediated protein degradation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene ID

8991

Gene Name (Vector)

selenium binding protein 1

Gene Symbol

SELENBP1

HGNC ID

HGNC:10719

ORF Size (aa)

1227

ORF Size (bp)

1227 bp

RefSeq ID

NM_003944

RefSeq Synonyms

NM_003944, NM_001258289, NM_001258288, BC032997, BC009084,

Species

human

UniGene ID

Hs.632460

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.