human RPL17 shRNA silencing AAV

Name
AAV-h-RPL17-shRNA

Cat No
shAAV-221606

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human RPL17.

shAAV-221606

AAV-h-RPL17-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RPL17 (ribosomal protein L17). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

L17; PD-1; RPL23

Description (Vector)

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL23 because the encoded protein shares amino acid identity with ribosomal protein L23 from Halobacterium marismortui; however, its official symbol is RPL17. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream C18orf32 (chromosome 18 open reading frame 32) gene.

Gene ID

6139

Gene Name (Vector)

ribosomal protein L17

Gene Symbol

RPL17

HGNC ID

HGNC:10307

ORF Size (aa)

555

RefSeq ID

NM_000985

RefSeq Synonyms

NM_001199345, NM_001199344, NM_001199343, NM_001199342, NM_001199341, NM_001199340, NM_001035006, NM_000985, BC106031, BC066324, BC066323, BC017831, BC000502,

Species

human

UniGene ID

Hs.485090

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.