human RASGRF2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human RASGRF2.
shAAV-220776
AAV-h-RASGRF2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human RASGRF2 (Ras protein specific guanine nucleotide releasing factor 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GRF2; RAS-GRF2
Description (Vector)
RAS GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. This gene encodes a calcium-regulated nucleotide exchange factor activating both RAS and RAS-related protein, RAC1, through the exchange of bound GDP for GTP, thereby, coordinating the signaling of distinct mitogen-activated protein kinase pathways.
Gene ID
5924
Gene Name (Vector)
Ras protein specific guanine nucleotide releasing factor 2
Gene Symbol
RASGRF2
HGNC ID
HGNC:9876
ORF Size (aa)
3714
ORF Size (bp)
3714 bp
RefSeq ID
NM_006909
RefSeq Synonyms
NM_006909, BC136296, BC126112,
Species
human
UniGene ID
Hs.162129
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.