mouse RASGRF2 shRNA silencing AAV

Name 
AAV-m-RASGRF2-shRNA
Cat No 
shAAV-270172
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Rasgrf2.

shAAV-270172
AAV-m-RASGRF2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Rasgrf2 (RAS protein-specific guanine nucleotide-releasing factor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
6330417G04Rik; AW048350; Grf2; Ras-GRF2
Description (Vector)
Functions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for GTP. Preferentially activates HRAS in vivo compared to RRAS based on their different types of prenylation. Functions in synaptic plasticity by contributing to the induction of long term potentiation.
Gene ID
19418
Gene Name (Vector)
RAS protein-specific guanine nucleotide-releasing factor 2
Gene Symbol
Rasgrf2
ORF Size (aa)
3567
ORF Size (bp)
3567 bp
RefSeq ID
NM_009027
RefSeq Synonyms
NM_009027, BC156258,
Species
mouse
UniGene ID
Mm.248630

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.