human RANBP17 shRNA silencing AAV

Name 
AAV-h-RANBP17-shRNA
Cat No 
shAAV-220704
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RANBP17.

shAAV-220704
AAV-h-RANBP17-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RANBP17 (RAN binding protein 17). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
50
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ran-binding protein 17
Description (eCommerce)
Ran-binding protein 17 (RanBP17) is a member of the importin-beta superfamily of nuclear transport receptors. The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex. The small GTPase RAN plays a key role in NLS-dependent protein import [taken from NCBI Entrez Gene (Gene ID: 64901)].
Description (Vector)
The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.(supplied by OMIM, Jul 2002)
Gene ID
64901
Gene Name (eCommerce)
RAN binding protein 17
Gene Name (Vector)
RAN binding protein 17
Gene Symbol
RANBP17
HGNC ID
HGNC:14428
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3264
ORF Size (bp)
3264 bp
Protein Name (eCommerce)
Ran-binding protein 17
RefSeq ID
NM_022897
RefSeq Synonyms
NM_022897, BC148559,
Research Areas
mRNA transport,RNA Transport,Transport
Research Areas (Faceted)
genetics,transcription_translation,cell_biology
Species
human
Target Sentence
Ran-binding protein 17 (RanBP17) is a member of the importin-beta superfamily of nuclear transport receptors. The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex. The small GTPase RAN plays a key role in NLS-dependent protein import [taken from NCBI Entrez Gene (Gene ID: 64901)].
UniGene ID
Hs.410810
UniProt ID (eCommerce)
Q9H2T7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.