human PTGS1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PTGS1.
shAAV-220256
AAV-h-PTGS1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PTGS1 (prostaglandin-endoperoxide synthase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS
Description (Vector)
This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.
Gene ID
5742
Gene Name (Vector)
prostaglandin-endoperoxide synthase 1
Gene Symbol
PTGS1
HGNC ID
HGNC:9604
ORF Size (aa)
1800
ORF Size (bp)
1800 bp
RefSeq ID
NM_000962
RefSeq Synonyms
NM_080591, NM_001271368, NM_001271367, NM_001271166, NM_001271165, NM_001271164, NM_000962, BC029840,
Species
human
UniGene ID
Hs.201978
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.