human PTGES3 shRNA silencing AAV

Name 
AAV-h-PTGES3-shRNA
Cat No 
shAAV-220246
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PTGES3.

shAAV-220246
AAV-h-PTGES3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PTGES3 (prostaglandin E synthase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
cPGES; cytosolic prostaglandin E synthase; cytosolic prostaglandin E2 synthase; Hsp90 co-chaperone; P23; progesterone receptor complex p23; prostaglandin E synthase 3; prostaglandin E synthase 3 (cytosolic); TEBP; telomerase-binding protein p23; unactive progesterone receptor, 23 kD
Description (eCommerce)
P23 is a molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15185].
Gene ID
10728
Gene Name (eCommerce)
prostaglandin E synthase 3
Gene Name (Vector)
prostaglandin E synthase 3
Gene Symbol
PTGES3
HGNC ID
HGNC:16049
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
483
ORF Size (bp)
483 bp
Protein Name (eCommerce)
Prostaglandin E synthase 3
RefSeq ID
NM_006601
RefSeq Synonyms
NM_006601, NM_001282605, NM_001282604, NM_001282603, NM_001282602, NM_001282601, BC003005,
Research Areas
Immunology,Metabolism/Metabolic Process,Protein Folding,Signal Transduction,Telomeric Maintenance
Research Areas (Faceted)
cell_biology,immunology,metabolism,signal_transduction
Species
human
Target Sentence
P23 is a molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15185].
UniGene ID
Hs.50425
UniProt ID (eCommerce)
Q15185

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.