human PSPN shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PSPN.
shAAV-220197
AAV-h-PSPN-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PSPN (persephin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PSP
Description (Vector)
PSPN is a neurotrophic factor, belonging to the GDNF family. Neurotrophic factors are important for the proper development and maintenance of the nervous system. These factors promote neuronal survival and can prevent the neuronal degeneration associated with injury, toxin exposure, or neurodegenerative disease. The encoded protein has amino acid similarity to its other family members, glial cell line-derived neurotrophic factor and neurturin. This gene product promotes the survival of ventral midbrain dopaminergic neurons in culture and prevents their degeneration after 6-hydroxydopamine treatment in vivo.
Gene ID
5623
Gene Name (Vector)
persephin
Gene Symbol
PSPN
HGNC ID
HGNC:9579
ORF Size (aa)
471
RefSeq ID
NM_004158
RefSeq Synonyms
NM_004158, BC156563, BC152717,
Species
human
UniGene ID
Hs.248159
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.