human PRKCDBP shRNA silencing AAV

Name 
AAV-h-PRKCDBP-shRNA
Cat No 
shAAV-219861
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PRKCDBP.

shAAV-219861
AAV-h-PRKCDBP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PRKCDBP (protein kinase C delta binding protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
caveolae-associated protein 3; cavin-3; HSRBC; PRKCDBP; protein kinase C delta binding protein; Protein kinase C delta-binding protein; sdr-related gene product that binds to c-kinase; serum deprivation response factor-related gene product that binds to C-kinase; SRBC
Description (eCommerce)
Serum deprivation response factor-related gene product that binds to C-kinase (SRBC) was identified as a binding protein of the protein kinase C, delta (PRKCD). The expression of this gene in cultured cell lines is strongly induced by serum starvation. The expression of this protein was found to be down-regulated in various cancer cell lines, suggesting the possible tumor suppressor function of this protein [taken from NCBI Entrez Gene (GeneID:112464)].
Description (Vector)
PRKCDBP was identified as a binding protein of the protein kinase C, delta (PRKCD). The expression of this gene in cultured cell lines is strongly induced by serum starvation. The expression of this protein was found to be down-regulated in various cancer cell lines, suggesting the possible tumor suppressor function of this protein.
Gene ID
112464
Gene Name (eCommerce)
caveolae associated protein 3
Gene Name (Vector)
protein kinase C delta binding protein
Gene Symbol
PRKCDBP
HGNC ID
HGNC:9400
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
786
Protein Name (eCommerce)
Protein kinase C delta-binding protein
RefSeq ID
NM_145040
RefSeq Synonyms
NM_145040, BC011585,
Research Areas
Cancer,Cell Biology,Tumor Suppressors/Oncoproteins
Research Areas (Faceted)
cancer,cell_biology
Species
human
Target Sentence
Serum deprivation response factor-related gene product that binds to C-kinase (SRBC) was identified as a binding protein of the protein kinase C, delta (PRKCD). The expression of this gene in cultured cell lines is strongly induced by serum starvation. The expression of this protein was found to be down-regulated in various cancer cell lines, suggesting the possible tumor suppressor function of this protein [taken from NCBI Entrez Gene (GeneID:112464)].
UniGene ID
Hs.434044
UniProt ID (eCommerce)
Q969G5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.