human PRDX4 shRNA silencing AAV

Name 
AAV-h-PRDX4-shRNA
Cat No 
shAAV-219780
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PRDX4.

shAAV-219780
AAV-h-PRDX4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PRDX4 (peroxiredoxin 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AOE37-2; AOE372; HEL-S-97n; PRX-4
Description (Vector)
PRDX4 is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB.
Gene ID
10549
Gene Name (Vector)
peroxiredoxin 4
Gene Symbol
PRDX4
HGNC ID
HGNC:17169
ORF Size (aa)
816
RefSeq ID
NM_006406
RefSeq Synonyms
NM_006406, BC016770, BC007107, BC003609,
Species
human
UniGene ID
Hs.83383

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.