human PRDX2 shRNA silencing AAV

Name
AAV-h-PRDX2-shRNA

Cat No
shAAV-219769

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human PRDX2.

shAAV-219769

AAV-h-PRDX2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PRDX2 (peroxiredoxin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MGC4104; NKEFB; PRP; PRX2; PRXII; TDPX1; TPX1; TSA;

Description (Vector)

PRDX2 encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The crystal structure of this protein has been resolved to 2.7 angstroms. Transcript variants encoding distinct isoforms have been identified for this gene.

Gene ID

7001

Gene Name (Vector)

peroxiredoxin 2

Gene Symbol

PRDX2

HGNC ID

HGNC:9353

ORF Size (aa)

597

RefSeq ID

NM_005809

RefSeq Synonyms

NM_181738, NM_005809, BC064138, BC039428, BC003022, BC000452,

Species

human

UniGene ID

Hs.432121

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.