human PPAP2C shRNA silencing AAV

Name
AAV-h-PPAP2C-shRNA

Cat No
shAAV-219501

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human PLPP2.

shAAV-219501

AAV-h-PPAP2C-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PLPP2 (phospholipid phosphatase 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

LPP2; PAP-2c; PAP2-g; PPAP2C

Description (Vector)

PPAP2C is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B). All three proteins contain 6 transmembrane regions, and a consensus N-glycosylation site. This protein has been shown to possess membrane associated PAP activity. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gene ID

8612

Gene Name (Vector)

phospholipid phosphatase 2

Gene Symbol

PLPP2

HGNC ID

HGNC:9230

ORF Size (aa)

867

RefSeq ID

NM_003712

RefSeq Synonyms

NM_177543, NM_177526, NM_003712, BC002806,

Species

human

UniGene ID

Hs.465506

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.