human PPAP2B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PLPP3.
shAAV-219500
AAV-h-PPAP2B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PLPP3 (phospholipid phosphatase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Dri42; LPP3; PAP2B; PPAP2B; VCIP
Description (Vector)
PPAP2B is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is a membrane glycoprotein localized at the cell plasma membrane. It has been shown to actively hydrolyze extracellular lysophosphatidic acid and short-chain phosphatidic acid. The expression of this gene is found to be enhanced by epidermal growth factor in Hela cells.
Gene ID
8613
Gene Name (Vector)
phospholipid phosphatase 3
Gene Symbol
PLPP3
HGNC ID
HGNC:9229
ORF Size (aa)
936
RefSeq ID
NM_003713
RefSeq Synonyms
NM_003713, BC009196,
Species
human
UniGene ID
Hs.715848
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.