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human POU4F3 shRNA silencing AAV

Name 
AAV-h-POU4F3-shRNA
Cat No 
shAAV-219485
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human POU4F3.

shAAV-219485
AAV-h-POU4F3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human POU4F3 (POU class 4 homeobox 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BRN3C; DFNA15; DFNA42; DFNA52
Description (Vector)
POU4F3 encodes a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. This protein is found in the retina and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in this gene are the cause of non-syndromic sensorineural deafness autosomal dominant type 15.
Gene ID
5459
Gene Name (Vector)
POU class 4 homeobox 3
Gene Symbol
POU4F3
HGNC ID
HGNC:9220
ORF Size (aa)
1017
ORF Size (bp)
1017 bp
RefSeq ID
NM_002700
RefSeq Synonyms
NM_002700, BC112207, BC104923,
Species
human
UniGene ID
Hs.553499

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.