human ENPP1 Over-expression AAV

Name
AAV-h-ENPP1

Cat No
AAV-207929

Availability
4-5 weeks

This is an AAV expressing Human ENPP1.

AAV-207929

AAV-h-ENPP1

Ready-to-use AAV expressing Human ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ARHR2; COLED; M6S1; NPP1; NPPS; PC-1; PCA1; PDNP1

Description (Vector)

ENPP1 is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance.

Gene ID

5167

Gene Name (Vector)

ectonucleotide pyrophosphatase/phosphodiesterase 1

Gene Symbol

ENPP1

HGNC ID

HGNC:3356

ORF Size (aa)

2622

ORF Size (bp)

2622 bp

RefSeq ID

NM_006208

RefSeq Synonyms

NM_006208, BC059375,

Species

human

UniGene ID

Hs.527295

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.