human POLE2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human POLE2.
shAAV-219360
AAV-h-POLE2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human POLE2 (DNA polymerase epsilon 2, accessory subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DNA polymerase epsilon subunit 2; DNA polymerase epsilon subunit B; DNA polymerase II subunit 2; DPE2; polymerase (DNA directed), epsilon 2 (p59 subunit); polymerase (DNA directed), epsilon 2, accessory subunit; polymerase (DNA) epsilon 2, accessory subunit
Description (eCommerce)
DNA Polymerase epsilon Subunit 2 (POLE2) participates in DNA repair and in chromosomal DNA replication [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P56282].
Gene ID
5427
Gene Name (eCommerce)
DNA polymerase epsilon 2, accessory subunit
Gene Name (Vector)
DNA polymerase epsilon 2, accessory subunit
Gene Symbol
POLE2
HGNC ID
HGNC:9178
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1509
ORF Size (bp)
1509 bp
Protein Name (eCommerce)
DNA polymerase epsilon subunit 2
RefSeq ID
NM_002692
RefSeq Synonyms
NM_002692, NM_001197331, NM_001197330, BC126220, BC126218, BC112962,
Research Areas
Cell Cycle,DNA Damage/Repair,Host-Virus Interactions,Telomeric Maintenance
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation,infectious_disease
Species
human
Target Sentence
DNA Polymerase epsilon Subunit 2 (POLE2) participates in DNA repair and in chromosomal DNA replication [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P56282].
UniGene ID
Hs.162777
UniProt ID (eCommerce)
P56282
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.