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human POFUT2 shRNA silencing AAV

Name 
AAV-h-POFUT2-shRNA
Cat No 
shAAV-219338
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human POFUT2.

shAAV-219338
AAV-h-POFUT2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human POFUT2 (protein O-fucosyltransferase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C21orf80; FUT13
Description (Vector)
Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530)-like repeats or thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 (PubMed 16464857)).(supplied by OMIM, Mar 2008)
Gene ID
23275
Gene Name (Vector)
protein O-fucosyltransferase 2
Gene Symbol
POFUT2
HGNC ID
HGNC:14683
ORF Size (aa)
1290
ORF Size (bp)
1290 bp
RefSeq ID
NM_015227
RefSeq Synonyms
NM_133635, NM_015227, BC064623,
Species
human
UniGene ID
Hs.592164

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.