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human POFUT1 shRNA silencing AAV

Name 
AAV-h-POFUT1-shRNA
Cat No 
shAAV-219337
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human POFUT1.

shAAV-219337
AAV-h-POFUT1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human POFUT1 (protein O-fucosyltransferase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
50
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DDD2; FUT12; O-Fuc-T; O-FucT-1; O-FUT; OFUCT1
Description (Vector)
POFUT1 encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Gene ID
23509
Gene Name (Vector)
protein O-fucosyltransferase 1
Gene Symbol
POFUT1
HGNC ID
HGNC:14988
ORF Size (aa)
585
RefSeq ID
NM_015352
RefSeq Synonyms
NM_172236, NM_015352, BC000582,
Species
human
UniGene ID
Hs.472409

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.