human PMM1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PMM1.
shAAV-219270
AAV-h-PMM1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PMM1 (phosphomannomutase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Sec53
Description (Vector)
Phosphomannomutase catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose, which is essential for N-linked glycosylation and thus the secretion of several glycoproteins as well as for the synthesis of glycosyl-phosphatidyl-inositol (GPI) anchored proteins.
Gene ID
5372
Gene Name (Vector)
phosphomannomutase 1
Gene Symbol
PMM1
HGNC ID
HGNC:9114
ORF Size (aa)
789
RefSeq ID
NM_002676
RefSeq Synonyms
NM_002676, BC016818, BC010855,
Species
human
UniGene ID
Hs.75835
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.