human PIK3R1 shRNA silencing AAV

Name
AAV-h-PIK3R1-shRNA

Cat No
shAAV-218955

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human PIK3R1.

shAAV-218955

AAV-h-PIK3R1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PIK3R1 (phosphoinositide-3-kinase regulatory subunit 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AGM7; GRB1; IMD36; p85; p85-ALPHA

Description (Vector)

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms.

Gene ID

5295

Gene Name (Vector)

phosphoinositide-3-kinase regulatory subunit 1

Gene Symbol

PIK3R1

HGNC ID

HGNC:8979

ORF Size (aa)

1365

ORF Size (bp)

1365 bp

RefSeq ID

NM_181504

RefSeq Synonyms

NM_181524, NM_181523, NM_181504, NM_001242466, BC094795, BC030815,

Species

human

UniGene ID

Hs.604502

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.