mouse PIK3R1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Pik3r1.
shAAV-268650
AAV-m-PIK3R1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Pik3r1 (phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
p50alpha; p55alpha; p85alpha; PI3K
Description (Vector)
Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.
Gene ID
18708
Gene Name (Vector)
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
Gene Symbol
Pik3r1
ORF Size (aa)
2175
ORF Size (bp)
2175 bp
RefSeq ID
NM_001077495
RefSeq Synonyms
NM_001077495, NM_001024955, BC051106, BC026146,
Species
mouse
UniGene ID
Mm.259333
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.