human PHF16 shRNA silencing AAV

Name 
AAV-h-PHF16-shRNA
Cat No 
shAAV-218805
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human JADE3.

shAAV-218805
AAV-h-PHF16-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human JADE3 (jade family PHD finger 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
jade family PHD finger protein 3; JADE-3; PHD finger protein 16; PHF16; protein Jade-3
Description (eCommerce)
PHD finger protein 16 (PHF16) is also known as JADE3. PHF16 is a component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q92613].
Description (Vector)
PHF16 is part of a gene cluster on chromosome Xp11.23. The encoded protein contains a zinc finger motif often found in transcriptional regulators, however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding the same protein.
Gene ID
9767
Gene Name (eCommerce)
jade family PHD finger 3
Gene Name (Vector)
jade family PHD finger 3
Gene Symbol
JADE3
HGNC ID
HGNC:22982
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2472
ORF Size (bp)
2472 bp
Protein Name (eCommerce)
Protein Jade-3
RefSeq ID
NM_014735
RefSeq Synonyms
NM_014735, NM_001077445, BC114487, BC113880,
Research Areas
Chromatin Remodeling,Histone Modification,Zinc-finger
Research Areas (Faceted)
cell_biology,genetics
Species
human
Target Sentence
PHD finger protein 16 (PHF16) is also known as JADE3. PHF16 is a component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q92613].
UniGene ID
Hs.371977
UniProt ID (eCommerce)
Q92613

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.