human PFN1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PFN1.
shAAV-218690
AAV-h-PFN1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PFN1 (profilin 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ALS18
Description (Vector)
PFN1 encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1.
Gene ID
5216
Gene Name (Vector)
profilin 1
Gene Symbol
PFN1
HGNC ID
HGNC:8881
ORF Size (aa)
423
RefSeq ID
NM_005022
RefSeq Synonyms
NM_005022, BC057828, BC015164, BC013439, BC006768, BC002475,
Species
human
UniGene ID
Hs.494691
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.