human PEBP1 shRNA silencing AAV

Name 
AAV-h-PEBP1-shRNA
Cat No 
shAAV-218590
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PEBP1.

shAAV-218590
AAV-h-PEBP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PEBP1 (phosphatidylethanolamine binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
epididymis luminal protein 210; epididymis secretory protein Li 34; epididymis secretory protein Li 96; HCNP; HCNPpp; HEL-210; HEL-S-34; HEL-S-96; hippocampal cholinergic neurostimulating peptide; neuropolypeptide h3; PBP; PEBP; PEBP-1; phosphatidylethanolamine-binding protein 1; prostatic binding protein; Prostatic-binding protein; raf kinase inhibitor protein; Raf kinase inhibitory protein; RKIP
Description (eCommerce)
Raf kinase inhibitor protein (RKIP) binds ATP, opioids and phosphatidylethanolamine. RKIP has lower affinity for phosphatidylinositol and phosphatidylcholine. it is a serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). RKIP inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P30086].
Gene ID
5037
Gene Name (eCommerce)
phosphatidylethanolamine binding protein 1
Gene Name (Vector)
phosphatidylethanolamine binding protein 1
Gene Symbol
PEBP1
HGNC ID
HGNC:8630
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
564
ORF Size (bp)
564 bp
Protein Name (eCommerce)
Phosphatidylethanolamine-binding protein 1
RefSeq ID
NM_002567
RefSeq Synonyms
NM_002567, BC031102, BC017396, BC008714,
Research Areas
Aging,Brain Development,Cardiology,Cardiovascular,Cell Cycle,EGFR Signaling,Golgi Apparatus,Interleukin Signaling,MAPK Signaling,Neurobiology,Neurodevelopment,Signal Transduction
Research Areas (Faceted)
cardiovascular,cell_biology,cell_cycle,developmental_biology,genetics,immunology,neurobiology,signal_transduction
Species
human
Target Sentence
Raf kinase inhibitor protein (RKIP) binds ATP, opioids and phosphatidylethanolamine. RKIP has lower affinity for phosphatidylinositol and phosphatidylcholine. it is a serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). RKIP inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P30086].
UniGene ID
Hs.433863
UniProt ID (eCommerce)
P30086

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.