human PANX1 shRNA silencing AAV

Name 
AAV-h-PANX1-shRNA
Cat No 
shAAV-218178
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PANX1.

shAAV-218178
AAV-h-PANX1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PANX1 (pannexin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MRS1; PX1; UNQ2529
Description (Vector)
PANX1 belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.
Gene ID
24145
Gene Name (Vector)
pannexin 1
Gene Symbol
PANX1
HGNC ID
HGNC:8599
ORF Size (aa)
1281
ORF Size (bp)
1281 bp
RefSeq ID
NM_015368
RefSeq Synonyms
NM_015368, BC016931,
Species
human
UniGene ID
Hs.591976

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.