human ELAVL3 Over-expression AAV

Name
AAV-h-ELAVL3

Cat No
AAV-207830

Availability
4-5 weeks

This is an AAV expressing Human ELAVL3.

AAV-207830

AAV-h-ELAVL3

Ready-to-use AAV expressing Human ELAVL3 (ELAV like RNA binding protein 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HUC; HUCL; PLE21

Description (Vector)

A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene ID

1995

Gene Name (Vector)

ELAV like RNA binding protein 3

Gene Symbol

ELAVL3

HGNC ID

HGNC:3314

ORF Size (aa)

705

ORF Size (bp)

705 bp

RefSeq ID

NM_001420

RefSeq Synonyms

NM_032281, NM_001420, BC011875,

Species

human

UniGene ID

Hs.1701

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.