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human OSBP shRNA silencing AAV

Name 
AAV-h-OSBP-shRNA
Cat No 
shAAV-217943
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human OSBP.

shAAV-217943
AAV-h-OSBP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human OSBP (oxysterol binding protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
OSBP1; oxysterol-binding protein 1
Description (eCommerce)
Oxysterol binding protein (OSBP) is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase [taken from NCBI Entrez Gene (Gene ID: 5007)].
Description (Vector)
Oxysterol binding protein is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase
Gene ID
5007
Gene Name (eCommerce)
oxysterol binding protein
Gene Name (Vector)
oxysterol binding protein
Gene Symbol
OSBP
HGNC ID
HGNC:8503
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2424
ORF Size (bp)
2424 bp
Protein Name (eCommerce)
Oxysterol-binding protein 1
RefSeq ID
NM_002556
RefSeq Synonyms
NM_002556, BC011581,
Research Areas
Golgi Apparatus,Metabolism/Metabolic Process,Transport
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
Oxysterol binding protein (OSBP) is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase [taken from NCBI Entrez Gene (Gene ID: 5007)].
UniGene ID
Hs.597091
UniProt ID (eCommerce)
P22059

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.