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human OSBP Over-expression AAV

Name 
AAV-h-OSBP
Cat No 
AAV-217943
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human OSBP.

AAV-217943
AAV-h-OSBP

Ready-to-use AAV expressing Human OSBP (oxysterol binding protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
OSBP1; oxysterol-binding protein 1
Description (eCommerce)
Oxysterol binding protein (OSBP) is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase [taken from NCBI Entrez Gene (Gene ID: 5007)].
Description (Vector)
Oxysterol binding protein is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase
Gene ID
5007
Gene Name (eCommerce)
oxysterol binding protein
Gene Name (Vector)
oxysterol binding protein
Gene Symbol
OSBP
HGNC ID
HGNC:8503
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2424
ORF Size (bp)
2424 bp
Protein Name (eCommerce)
Oxysterol-binding protein 1
RefSeq ID
NM_002556
RefSeq Synonyms
NM_002556, BC011581,
Research Areas
Golgi Apparatus,Metabolism/Metabolic Process,Transport
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
Oxysterol binding protein (OSBP) is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase [taken from NCBI Entrez Gene (Gene ID: 5007)].
UniGene ID
Hs.597091
UniProt ID (eCommerce)
P22059

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.