human ORC4L shRNA silencing AAV

Name
AAV-h-ORC4L-shRNA

Cat No
shAAV-217927

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human ORC4.

shAAV-217927

AAV-h-ORC4L-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ORC4 (origin recognition complex subunit 4). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ORC4L; ORC4P

Description (Vector)

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene.

Gene ID

5000

Gene Name (Vector)

origin recognition complex subunit 4

Gene Symbol

ORC4

HGNC ID

HGNC:8490

ORF Size (aa)

1311

ORF Size (bp)

1311 bp

RefSeq ID

NM_002552

RefSeq Synonyms

NM_181742, NM_181741, NM_002552, NM_001190882, NM_001190881, NM_001190879, BC014847, BC005388,

Species

human

UniGene ID

Hs.558364

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.