human EIF3M Over-expression AAV

Name 
AAV-h-EIF3M
Cat No 
AAV-207763
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human EIF3M.

AAV-207763
AAV-h-EIF3M

Ready-to-use AAV expressing Human EIF3M (eukaryotic translation initiation factor 3 subunit M). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
B5; B5 receptor; dendritic cell protein; eIF3m; eukaryotic translation initiation factor 3 subunit M; fetal lung protein B5; GA17; hfl-B5; PCI domain containing 1 (herpesvirus entry mediator); PCI domain-containing protein 1; PCID1; TANGO7; transport and golgi organization 7 homolog
Description (eCommerce)
EIF3M is part of the eurkaryotic translation initiation factor 3 complete (eIF-3) required for protein synthesis. Elevated levels of EIF3M are present in cancer cell lines. Inactivation of EIF3M has been shown to interfere with translation of herpes virus mRNAs by preventing the association of mRNAs with the ribosomes [taken from NCBI Entrez Gene (Gene ID: 10480)].
Description (Vector)
EIF3M encodes a protein that is part of the eurkaryotic translation initiation factor 3 complete (eIF-3) required for protein synthesis. Elevated levels of the encoded protein are present in cancer cell lines. Inactivation of the encoded protein has been shown to interfere with translation of herpes virus mRNAs by preventing the association of mRNAs with the ribosomes. A pseudogene of this gene is located on the X chromosome.
Gene ID
10480
Gene Name (eCommerce)
eukaryotic translation initiation factor 3 subunit M
Gene Name (Vector)
eukaryotic translation initiation factor 3 subunit M
Gene Symbol
EIF3M
HGNC ID
HGNC:24460
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1125
ORF Size (bp)
1125 bp
Protein Name (eCommerce)
Eukaryotic translation initiation factor 3 subunit M
RefSeq ID
NM_006360
RefSeq Synonyms
NM_006360, NM_001307929, BC051292, BC019103,
Research Areas
Immunology,T-cell Receptor Signaling,Translational Control
Research Areas (Faceted)
cell_biology,immunology,signal_transduction,transcription_translation
Species
human
Target Sentence
EIF3M is part of the eurkaryotic translation initiation factor 3 complete (eIF-3) required for protein synthesis. Elevated levels of EIF3M are present in cancer cell lines. Inactivation of EIF3M has been shown to interfere with translation of herpes virus mRNAs by preventing the association of mRNAs with the ribosomes [taken from NCBI Entrez Gene (Gene ID: 10480)].
UniGene ID
Hs.502244
UniProt ID (eCommerce)
Q7L2H7

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.