human EIF3J Over-expression AAV

Name 
AAV-h-EIF3J
Cat No 
AAV-207757
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human EIF3J.

AAV-207757
AAV-h-EIF3J

Ready-to-use AAV expressing Human EIF3J (eukaryotic translation initiation factor 3 subunit J). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
eIF3 p35; eIF-3-alpha; eIF3-alpha; eIF3j; eIF3-p35; EIF3S1; Eukaryotic translation initiation factor 3 subunit 1; eukaryotic translation initiation factor 3 subunit J; eukaryotic translation initiation factor 3, subunit 1 (alpha, 35kD)
Description (eCommerce)
Eukaryotic initiation factor 3 subunit J (eIF3J) is one of at least 13 non-identical protein subunits of eukaryotic initiation factor 3 (eIF3). eIF3 is the largest eIF (~650 kDa) and functions to facilitate binding of the 40S ribosomal subunit to the 5’-end of cellular mRNAs near the cap structure (m7GpppN). eIF3J is proposed to act as a factor that further stabilizes the interaction between eIF3 and the ribosome.
Description (Vector)
Eukaryotic initiation factor-3 (EIF3) has a molecular mass of about 600 kD and contains 13 nonidentical protein subunits, including EIF3J. EIF3 plays a central role in binding of initiator methionyl-tRNA and mRNA to the 40S ribosomal subunit to form the 40S initiation complex (Fraser et al., 2004 (PubMed 14688252); Fraser et al., 2007 (PubMed 17588516)).(supplied by OMIM, Mar 2008)
Gene ID
8669
Gene Name (eCommerce)
eukaryotic translation initiation factor 3 subunit J
Gene Name (Vector)
eukaryotic translation initiation factor 3 subunit J
Gene Symbol
EIF3J
HGNC ID
HGNC:3270
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
777
ORF Size (bp)
777 bp
Protein Name (eCommerce)
Eukaryotic translation initiation factor 3 subunit J
RefSeq ID
NM_003758
RefSeq Synonyms
NM_003758, NM_001284336, NM_001284335, BC002719,
Research Areas
Gene Expression,Metabolism/Metabolic Process,mRNA Binding,RNA Transport,Translational Control
Research Areas (Faceted)
genetics,transcription_translation,metabolism,cell_biology
Species
human
Target Sentence
Eukaryotic initiation factor 3 subunit J (eIF3J) is one of at least 13 non-identical protein subunits of eukaryotic initiation factor 3 (eIF3). eIF3 is the largest eIF (~650 kDa) and functions to facilitate binding of the 40S ribosomal subunit to the 5’-end of cellular mRNAs near the cap structure (m7GpppN). eIF3J is proposed to act as a factor that further stabilizes the interaction between eIF3 and the ribosome.
UniGene ID
Hs.404056
UniProt ID (eCommerce)
O75822

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.