human NT5C shRNA silencing AAV

Name
AAV-h-NT5C-shRNA

Cat No
shAAV-217130

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human NT5C.

shAAV-217130

AAV-h-NT5C-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NT5C (5′, 3′-nucleotidase, cytosolic). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

cdN; DNT; dNT-1; DNT1; HEL74; P5N2; PN-I; PN-II; UMPH2

Description (Vector)

NT5C encodes a nucleotidase that catalyzes the dephosphorylation of the 5' deoxyribonucleotides (dNTP) and 2'(3')-dNTP and ribonucleotides, but not 5' ribonucleotides. Of the different forms of nucleotidases characterized, this enzyme is unique in its preference for 5'-dNTP. It may be one of the enzymes involved in regulating the size of dNTP pools in cells. Alternatively spliced transcript variants have been found for this gene.

Gene ID

30833

Gene Name (Vector)

5', 3'-nucleotidase, cytosolic

Gene Symbol

NT5C

HGNC ID

HGNC:17144

ORF Size (aa)

606

RefSeq ID

NM_014595

RefSeq Synonyms

NM_014595, NM_001252377, BC022334, BC017454, BC008183,

Species

human

UniGene ID

Hs.67201

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.