human NRTN shRNA silencing AAV

Name
AAV-h-NRTN-shRNA

Cat No
shAAV-217103

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human NRTN.

shAAV-217103

AAV-h-NRTN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NRTN (neurturin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

NTN

Description (Vector)

Neurturin is a member of the TGF-beta subfamily, TRN. This gene signals through RET and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease.

Gene ID

4902

Gene Name (Vector)

neurturin

Gene Symbol

NRTN

HGNC ID

HGNC:8007

ORF Size (aa)

594

RefSeq ID

NM_004558

RefSeq Synonyms

NM_004558, BC137400, BC137399,

Species

human

UniGene ID

Hs.234775

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.