human NR4A1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human NR4A1.
shAAV-217056
AAV-h-NR4A1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human NR4A1 (nuclear receptor subfamily 4 group A member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GFRP1; HMR; N10; NAK-1; NGFIB; NP10; NUR77; TR3
Description (Vector)
NR4A1 encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
3164
Gene Name (Vector)
nuclear receptor subfamily 4 group A member 1
Gene Symbol
NR4A1
HGNC ID
HGNC:7980
ORF Size (aa)
1797
ORF Size (bp)
1797 bp
RefSeq ID
NM_002135
RefSeq Synonyms
NM_173157, NM_002135, NM_001202234, NM_001202233, BC016147,
Species
human
UniGene ID
Hs.524430
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.