human NFKBIA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human NFKBIA.
shAAV-216647
AAV-h-NFKBIA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human NFKBIA (NFKB inhibitor alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
IKBA; MAD-3; NFKBI
Description (Vector)
NFKBIA encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
Gene ID
4792
Gene Name (Vector)
NFKB inhibitor alpha
Gene Symbol
NFKBIA
HGNC ID
HGNC:7797
ORF Size (aa)
954
ORF Size (bp)
954 bp
RefSeq ID
NM_020529
RefSeq Synonyms
NM_020529, BC004983, BC002601,
Species
human
UniGene ID
Hs.81328
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.