human MTR shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MTR.
shAAV-216044
AAV-h-MTR-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MTR (5-methyltetrahydrofolate-homocysteine methyltransferase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
cblG; HMAG; MS
Description (Vector)
MTR encodes the enzyme 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G.
Gene ID
4548
Gene Name (Vector)
5-methyltetrahydrofolate-homocysteine methyltransferase
Gene Symbol
MTR
HGNC ID
HGNC:7468
ORF Size (aa)
3798
ORF Size (bp)
3798 bp
RefSeq ID
NM_000254
RefSeq Synonyms
NM_001291940, NM_001291939, NM_000254, BC144097, BC144095, BC136440, BC130616,
Species
human
UniGene ID
Hs.498187
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.