human MTMR14 shRNA silencing AAV

Name 
AAV-h-MTMR14-shRNA
Cat No 
shAAV-216014
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MTMR14.

shAAV-216014
AAV-h-MTMR14-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MTMR14 (myotubularin related protein 14). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C3orf29
Description (Vector)
MTMR14 encodes a myotubularin-related protein. The encoded protein is a phosphoinositide phosphatase that specifically dephosphorylates phosphatidylinositol 3,5-biphosphate and phosphatidylinositol 3-phosphate. Mutations in this gene are correlated with autosomal dominant centronuclear myopathy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 18.
Gene ID
64419
Gene Name (Vector)
myotubularin related protein 14
Gene Symbol
MTMR14
HGNC ID
HGNC:26190
ORF Size (aa)
1797
ORF Size (bp)
1797 bp
RefSeq ID
NM_022485
RefSeq Synonyms
NM_022485, NM_001077526, NM_001077525, BC050626, BC035690, BC025952, BC001674,
Species
human
UniGene ID
Hs.475382

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.