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human DAOA shRNA silencing Adenovirus

Name 
Ad-h-DAOA-shRNA
Cat No 
shADV-206587
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human DAOA.

shADV-206587
Ad-h-DAOA-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human DAOA (D-amino acid oxidase activator). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
LG72; SG72
Description (Vector)
DAOA encodes a protein that may function as an activator of D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Studies also suggest that one encoded isoform may play a role in mitochondrial function and dendritic arborization. Polymorphisms in this gene have been implicated in susceptibility to schizophrenia and bipolar affective disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
267012
Gene Name (Vector)
D-amino acid oxidase activator
Gene Symbol
DAOA
HGNC ID
HGNC:21191
ORF Size (aa)
462
RefSeq ID
NM_172370
RefSeq Synonyms
NM_172370, NM_001161814, NM_001161812, BC121091,
Species
human
UniGene ID
Hs.381382

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.