human MST1 shRNA silencing AAV

Name
AAV-h-MST1-shRNA

Cat No
shAAV-215933

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human MST1.

shAAV-215933

AAV-h-MST1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MST1 (macrophage stimulating 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

D3F15S2; DNF15S2; HGFL; MSP; NF15S2

Description (Vector)

MST1 contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds.

Gene ID

4485

Gene Name (Vector)

macrophage stimulating 1

Gene Symbol

MST1

HGNC ID

HGNC:7380

ORF Size (aa)

2136

ORF Size (bp)

2136 bp

RefSeq ID

NM_020998

RefSeq Synonyms

NM_020998, BC048330,

Species

human

UniGene ID

Hs.512587

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.