human EDEM2 Over-expression AAV

Name 
AAV-h-EDEM2
Cat No 
AAV-207559
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human EDEM2.

AAV-207559
AAV-h-EDEM2

Ready-to-use AAV expressing Human EDEM2 (ER degradation enhancing alpha-mannosidase like protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bA4204.1; C20orf31; C20orf49
Description (Vector)
In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 (PubMed 15537790)).(supplied by OMIM, Mar 2008)
Gene ID
55741
Gene Name (Vector)
ER degradation enhancing alpha-mannosidase like protein 2
Gene Symbol
EDEM2
HGNC ID
HGNC:15877
ORF Size (aa)
1737
ORF Size (bp)
1737 bp
RefSeq ID
NM_018217
RefSeq Synonyms
NM_018217, NM_001145025, BC016184, BC001371,
Species
human
UniGene ID
Hs.356273

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.