human EDA2R Over-expression AAV

Name 
AAV-h-EDA2R
Cat No 
AAV-207550
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human EDA2R.

AAV-207550
AAV-h-EDA2R

Ready-to-use AAV expressing Human EDA2R (ectodysplasin A2 receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EDA-A2R; EDAA2R; TNFRSF27; XEDAR
Description (Vector)
EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Alternatively spliced transcript variants have been found for this gene.
Gene ID
60401
Gene Name (Vector)
ectodysplasin A2 receptor
Gene Symbol
EDA2R
HGNC ID
HGNC:17756
ORF Size (aa)
894
ORF Size (bp)
894 bp
RefSeq ID
NM_021783
RefSeq Synonyms
NM_021783, NM_001324206, NM_001324205, NM_001324204, NM_001324202, NM_001324201, NM_001324199, NM_001242310, NM_001199687, BC034919,
Species
human
UniGene ID
Hs.302017

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.