human ECEL1 Over-expression AAV

Name 
AAV-h-ECEL1
Cat No 
AAV-207529
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ECEL1.

AAV-207529
AAV-h-ECEL1

Ready-to-use AAV expressing Human ECEL1 (endothelin converting enzyme like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DA5D; DINE; ECEX; XCE
Description (Vector)
ECEL1 encodes a member of the M13 family of endopeptidases. In general, M13 family members are zinc-containing type II integral-membrane proteins that are important regulators of neuropeptide and peptide hormone activity. ECEL1 is expressed specifically in the central nervous system and its protein localizes predominately to the endoplasmic reticulum or, in trace amounts, to the cell surface. Disruption of this gene in mouse embryonic stem cells results in neonatal lethality due to respiratory failure shortly after birth. Based on the specific expression of this gene and the phenotype of the gene deficiency in mouse embryos, it is suggested that this protein plays a critical role in neural regulation of the respiratory system. ECEL1 has multiple pseudogenes.
Gene ID
9427
Gene Name (Vector)
endothelin converting enzyme like 1
Gene Symbol
ECEL1
HGNC ID
HGNC:3147
ORF Size (aa)
2328
ORF Size (bp)
2328 bp
RefSeq ID
NM_004826
RefSeq Synonyms
NM_004826, NM_001290787, BC050453,
Species
human
UniGene ID
Hs.26880

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.