human MDK shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MDK.
shAAV-215218
AAV-h-MDK-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MDK (midkine (neurite growth-promoting factor 2)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ARAP; MK; NEGF2
Description (Vector)
MDK encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth, migration, and angiogenesis, in particular during tumorigenesis. MDK has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
Gene ID
4192
Gene Name (Vector)
midkine (neurite growth-promoting factor 2)
Gene Symbol
MDK
HGNC ID
HGNC:6972
ORF Size (aa)
432
RefSeq ID
NM_002391
RefSeq Synonyms
NM_002391, NM_001270552, NM_001270551, NM_001270550, NM_001012334, NM_001012333, BC011704,
Species
human
UniGene ID
Hs.82045
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.